Deadly friends

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Deadly ingestions.

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The complement inhibitor C4b-binding protein (C4BP) prevents necrotic cells from spilling their pro-inflammatory guts, according to a study on page 1937. Trouw and colleagues now show that C4BP and its binding partner, anticoagulant protein S (PS), cooperate to grab onto necrotic cells and to inhibit the release of cellular DNA. C4BP short-circuits the complement cascade by binding to the activ...

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How deadly is the "deadly quartet"? A post-CABG evaluation.

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ژورنال

عنوان ژورنال: Nature Reviews Microbiology

سال: 2020

ISSN: 1740-1526,1740-1534

DOI: 10.1038/s41579-020-0371-6